Metabolomics for cancer research – Theory and practice

Semester: Spring
|
Year offered: 2024

Course Description
The field of cancer metabolism has grown tremendously in the past decade, contributing major advancements in our understanding of how to diagnose and treat tumors. Despite this, some of the tools required to study cancer metabolism remain out of reach for many labs. This is particularly true for metabolomics, as it requires deep prior knowledge and sophisticated instrumentation.

This course is designed to acquaint participants with principles and practice of cancer metabolism from the perspective of metabolomics. This course will introduce a major tool in the cancer metabolism field - metabolomics by LC-MS. Participants will get a first-hand theoretical knowledge and practical experience on designing, analyzing, and presenting mass spectrometry-based metabolomics experiments. The course will have a “hands-on” component and will provide an opportunity to incorporate participants’ own samples. For more details about the sessions see attached PDF.

Course Objectives

  1. Understand the fundamental concepts of LC-MS metabolomics
  2. Collect, analyze, and visualize LC-MS metabolomics data
  3. Compare targeted and untargeted LC-MS workflows
  4. Use the tools to visualize and communicate your data effectively

Course Directors | Boryana Petrova, PhD, boryana.petrova@childrens.harvard.edu
Curriculum Advisor | Jelena Patrnogić, PhD, jelena_patrnogic@hms.harvard.edu

NOTE this will be the last time we offer the course in this format and with Boryana Petrova, PhD as the Course Director. 

Enrollment limit
This course is limited to 8 participants.

Milestone Credit
Priority will be given to graduate students taking the course for credit. In order to receive credit, students must attend all sessions and complete all assignments, including the homework assignment (see details for session three in the attached PDF). Postdocs can register, too and they will be granted access to the course as space allows. More information about Milestone Credit can be found here.

Session dates, times & location
Session One
Tuesday February 20th, 9am-4pm, lunch will be provided
Ender’s 10th floor conference room (please bring ID, restricted access to building).

Session Two
Thursday February 22nd, 1pm-5pm, coffee and snacks will be provided.

Ender’s 10th floor conference room (please bring ID, restricted access to building).

Session Three:
Thursday February 29th, 1pm-5pm, coffee and snacks will be provided.

Ender’s 10th floor conference room (please bring ID, restricted access to building).

For more details about the sessions see attached PDF. 

REGISTER HERE by February 9