Applying the Concepts from Translational Discoveries





Course Description
Translational research has many definitions. Broadly, it is considered any investigation that can lead to clinical impact. In this course, we will use bench to bedside vignettes as a backdrop for interactive discussions. We will emphasize cancer dependency, targeted therapy, and resistance mechanisms to help facilitate problem-solving discussions. In particular, we will walk through the discovery of BCR-ABL inhibitors for chronic myelogenous leukemia and next generation anti-androgens for prostate cancer. The course will include group discussions and assignments designed to reinforce the key concepts from each session.

Course Objectives

  • Recognize the translational impact of thoughtful and rigorous basic science research
  • Describe examples of successful translational research and conceptual advances that led to biomedical breakthroughs
  • Analyze problem-solving in translational research
  • Connect translational research with your own project

Session dates, times & location
In order to receive credit, registered students must attend all sessions and complete the assignments. The course will take place in person.*

Session One Monday March 21, 2:30-4pm, TMEC 106
Session Two Tuesday March 22, 2:30-4pm, TMEC 306
Session Three Monday March 28, 2:30-4pm, TMEC 106
Session Four Tuesday March 29, 2:30-4pm, TMEC 306

For detailed information about the sessions - see attached document (2022 Nanocourse_Applying the Concepts from Translational Discoveries). 

Course Director
Nilay Sethi, MD, PhD

Curriculum Fellow
Jelena Patrnogić, PhD

*Physical Distancing
The HMS policy for in-person courses is that vaccinated individuals need not maintain any physical distancing, but that masks are required for indoor activities. Students who are not comfortable with this arrangement are asked to approach the course director or a member of the instructional staff before the first meeting to discuss alternate arrangements. Reasons not to be comfortable may include not being vaccinated, having a medical issue that makes one more vulnerable, or being in close contact with an immunocompromised individual.



2022 Nanocourse_Applying the Concepts from Translational Discoveries109 KB